综述了ASD合并PAH的诊疗进展。研究纳入386例ASD-PAH患者，肺血管阻力（PVR）<5 Wood单位组手术/封堵后5年生存率98%，PVR 5-8 Wood单位组经靶向治疗后手术的5年生存率89%，PVR>8 Wood单位组仅62%。推荐PVR>5 Wood单位者先接受3-6个月靶向药物治疗…
一项纳入1420例ASD患者的对比研究（封堵组820例，外科组600例）显示，10年随访期间介入封堵组和外科组在全因死亡（1.2% vs 0.8%，p=0.45）、主要心脑血管事件（2.1% vs 1.7%，p=0.38）方面无显著差异。介入封堵组住院时间显著缩短（2.3天 vs 5.7天，p<0.…
Contemporary early mortality for complete TOF repair in infants is approximately 1-3% in major centers.…
Adults with repaired TOF demonstrate reduced exercise capacity and lower quality of life scores, with RV dysfunction being the strongest predictor.…
Pulmonary valve replacement after TOF repair results in significant reduction of RV volumes and improvement in exercise capacity.…
Late morbidity after TOF repair is dominated by pulmonary regurgitation, right ventricular dilation, arrhythmias, and reoperation.…
Tetralogy of Fallot is the most common cyanotic congenital heart disease, with repair outcomes showing 30-year survival exceeding 85%.…
Children undergoing ASO for TGA have lower scores on neurodevelopmental assessments compared to population norms, highlighting the need for long-term …
Balloon atrial septostomy remains a critical preoperative intervention in TGA with restrictive atrial septum, significantly improving survival before …
Prenatal diagnosis of TGA has improved early outcomes by reducing preoperative acidosis and end-organ damage.…